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Take Desvenlafaxine exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take Pristiq in larger or smaller amounts or for longer than recommended.

You may take Desvenlafaxine with or without food. Take the medicine at the same time each day.

Do not crush, chew, or break an extended-release tablet. Swallow it whole.

It may take several weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve.

Do not stop using Desvenlafaxine suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using Pristiq.

Your blood pressure will need to be checked often.

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